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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd3acc966b1001e3b268b5e156cd09354201458d0f394d15787e5d42fcd47cbc0' 
  AND token = '6OTRvOlT8kK6jWejPu4EBNcPi7qVX3aeZzELFzkubZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}