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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '242f0f62179d4a4cdba9d469e925316295213ed83af332ee168b1988dc375bf8' 
  AND token = 'T3FdJQtbIU8Ny4yKX3ttrBb8QMoFuTe7xzlLCeuRvSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}