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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '05a9d7fdd9d648e028daf330b5ed02d73fc7f8771c6e6616d9b14d5344afb49f' 
  AND token = '4Ay2423ukoF+wUSpvYnbMTiKYTtMoFSqkIIdu75eds4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}