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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '66514f627e9fe8f811efa82960d48e1a1dbe531a91aa394dcb0badfa60aab9d8' 
  AND token = '/Y05FF/8xMAQI1R2QdxF8aZFeUZlWF2B05XZFbvLJPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}