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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3351df49f076ad450e2b8c9f37170c6672bc2714cc64159e8342df4caaf0aecc' 
  AND token = 'K14M1Pbza20pohSE2V6hXtPAbD4kXsi0MAqHykw5MFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}