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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '24168078f140dc54451cfc87d331eb7d4c441c2e1848dd19f4c7a8f99b476622' 
  AND token = 'Ej1sadA9ZtrxAOssQO0Cs43poyRQ+C2N8Xflhp0xz1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}