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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cfdf0e6a95e94a633c83ce63521c716234681a1dc87abd5cff8e010d8715b407' 
  AND token = 'xqab9awyjZ0naf/SBNYurNe8g59Q1kgG4sXJcfP95UA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}