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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e9e1a172855badbfde5a8063ff69412c7bcf710a3b176bfc95a4342140342448' 
  AND token = 'u58bmQVGUW5QiP4RKWVOGHfT1xaSFPzW2PGwNG9e8uU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}