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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f255de1199a21a4d29a0e286298e499c21707f8c053f8c00216a1ab161020908' 
  AND token = '3LELPBF5qSO/DcnNPBKhloWQB2hSWq14h6YjlIlxV04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}