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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2e00788fdefd811dd6f031150544f0e2db543d5ed33da7c0a12fcda676f77b29' 
  AND token = '7V1PATlGztAdX9lRsiysf8UZWu/adV7BoSloIkvpAvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}