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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2b1a91433f73df94f04a975cee5ee747301c15cf6eaa8b4291122ae1f4c395d2' 
  AND token = 'HKClZySGfg7ATQxOiESUQWTBolRdr0+GKf0UlB4LsmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}