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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0743677bd4b93f1b46d442f22223cc2bef02b807aeaad010029e26149be2f12f' 
  AND token = 'DUVH+e/xxDxEhc2V79jaQJQkZE67I8KB8MYeAAp9y/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}