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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8e0748a61ed4768dc55404a542d9ff7e1b9c1319e91ba8789f9ce74b07160666' 
  AND token = '/yOBm+UOmfbW13AReu7YUsnyAJZ6mPaaLjtNTSgeJmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}