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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '21c500d57e3b3d1bdf9bec3d729fa18df9c76069855fd50a37a3a786601758bc' 
  AND token = 'mERi+N5KI31MRwVHDbygDXOFsLNJlZzz0ZxZcDTn2Do=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}