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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2469641da7f704476c64cf1de1d6024d797b56c8d1a6600edc55845d0151e4c0' 
  AND token = 'QmXBG1XJEXwojvAATQNN1ovgJUF2h7rCCGARunhhYvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}