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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'fc52d3d940e62a2dab55ded9817b7e1a41866f5cb50c37a84b6169adb9db3272' 
  AND token = 'LjH2tmlFhxEnPDUuVicApFaiT23ov4ii/Ds0Zax3Bq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}