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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e3cd0ed5eb60887a48716ae8fc875e6b53f129729e7ecfab930fd2713c2d1b3f' 
  AND token = '22I+3C7VjQ6pT2RfWh3qDtjE3sugDUcEYWGhhAyBi7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}