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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6a96880159bb50f51e38c57c1c3fb99eed68c5015df2858115b771f52c22eb8c' 
  AND token = 'WUwBnIHDWZT1I7EaPOoO5PsPSDsg1CFcR/mUovfAGJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}