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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1bd41b3e11d9e6de0665afa6aa2ba7a480429351512f398d522531c3b3d8d620' 
  AND token = 'WNmLwwVVxJUVnI45rTt9JxIpweJTSZVcBl/+axuAsfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}