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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4f4f9943d7cfedfd0803f4b18db234b9ec94211c7f6d3addd429bb46a3e39862' 
  AND token = 'AT+2qzkOJEOIrZEd4m1pnQ/LjxW9QahBMOitaan2ojI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}