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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3800864803255132c80c1a98448897c5f2c3c839241e28ecceb5080c4365255d' 
  AND token = 'E81aHWNbT8h4ENTgxmvXjh6eySkaHVUeX1yHdCoTpB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}