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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ca8f76883cd48ed235f5fe20c61833af6e144b042656c2f171bde204dcd1b8bf' 
  AND token = 'Y8CggBAggtiqPMl5fCu+uYSR0AN4uW2IlNWapBpgF4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}