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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e2a1bc28a095ff0a3a010362e79aabf1c8ab277c63ac0376d1604a96b05b6329' 
  AND token = 'SSPE4x7IlIUukB55baZAzTi63N4VKjgX+3CF442w1ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}