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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '299f2c25e50fd7852e048da5a1fc60246e6121a3fc4b7bcb36c5a405a0f66dde' 
  AND token = 'KbyCQbOXXXmIWaiogrwknfNcyX/9YMiyPjG6SfdXTMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}