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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c509c4637c6deae685306a0555b9bceb9dbcfd1dbb356bd15421392a936009bd' 
  AND token = '0JJ+IpXyhO+Z+PS6x/OFqhsN9dq0S3MNYX0EG2mIZMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}