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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5af7c7d03bc4dff26e02478a65cdce1be2c4e06ab24587143b018d0f4a29f820' 
  AND token = 'G2Yy4NsWwlaw55FsNeZ1WTpLP62hvsXryHGubxAcUGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}