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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ab161b68c3d8cc02092033f0cf489e62f16252db3aa4750a0393ad84c9423112' 
  AND token = 'CInWo0ELQyUGPLIygM00mHT/m7JDQJT4F7atZXtMQQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}