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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e1c3512b613a1a779342914f0fe4a32fe8a46cfbfad1b4c4254450daaa4170d9' 
  AND token = '4p+dk4VIjeX9A1jGsibvtg3xAMaU9i1TKGfKP8AzSCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}