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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7affed74f27a34796dab6382dd935e544995c150d274d058939e7fae31340216' 
  AND token = '0oIu9i8H/Gp6s6iSCu9CylidWW1RcL2N/nDuSm3EDqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}