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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '72aba9a9c4b216f00ad456defe31470478f2a7cc66532e1d52cd98daf85d54f4' 
  AND token = 'WgmOrm7H+c95hFG27GIx7mabEx5lM5NfXwApUsgozx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}