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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '267134057436de887edfd0c97d2af5e675455f2bc5e07e5a1f12be9b2fad3ac0' 
  AND token = '9pyTNQRXOh1HqkD52FYqME9lOQKANFWJodAPFhiN4/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}