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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7b00bd463ee97ef3e6a64478452687149992af1a0a6c313763b7ef6bcf223498' 
  AND token = 'vrmAYmFQb2kiNJtFXmpk79vheVEnnw4UDdiWEEnL59Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}