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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8ecf67830620b2d94da3635757d712336fefd925ff9db494005f48191722dc54' 
  AND token = '0RjADpimxwXoRZ34DqqbAgeuCrbEIuDJ4IlLoXjkAb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}