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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5c90274024692f9cd32cedc5dd8422e1644237ef22b8192f032c6e833704775d' 
  AND token = 'AaWU/nA6draQS4sjyNubopgQ8TpCFUV5/G0ocfT6wIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}