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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '39a0be6164c575fd4b163a400e6659f5365003987e80ed268f75c999a2241385' 
  AND token = '2uf8EPWlmD6YccbULcipkD9gS6IR4AcgohyKaZyEoUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}