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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '004dbde156a55b79b85ac91360c825302dd3f938021aba6d311c1eed0f7aaf19' 
  AND token = 'WZGjy0Qx+gWytFYv0+7X4HXhN3rYOUT67+0yQQyZn7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}