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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8c6fb39754fcb42d532d91d053bb682f321b07c92960e55af26b8b9afeea7f8c' 
  AND token = 'XCWMzno8Me7+AZc40Rx0lsGBy7SdUTrxfCPUFL1Z+Hk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}