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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '21ab6aaa5b450ae8eee5d484b8b83b658b9a1000eb208f8f1b60e12e206b8f18' 
  AND token = '06YVa38I8kI4seFkfKEBHgJvnkJVdYd3iRLC/T5eVtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}