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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '414cd4d9ce68229c70e2372b69cb42a1a911faa2d176bfcc79fe48c9f9aaad3b' 
  AND token = 'c1Wdp3fcRHfMd0hRb+khYPmtAjqDRg6QmpXgJSVht3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}