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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '72724d56436e603718e6dc463c3a39498e8860d0a3625dfd07e37b8a971d0367' 
  AND token = 'XQe5N0lz7Rdv5JwP0uiUTdhyby33bQDZBm/cn0wb4Sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}