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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f87e1864764bcd46739e993c7374de479b9a3ea96d71b1ae4d6a7e3a234c13cc' 
  AND token = '4IOHhHHFbrSEO5hRCAvQhqlN0+KDs1FaYf7YusyuaL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}