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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '457e52f0b4eabe49f07b898aac4fe24e9a51b051edaf393f0af777afad9f6c9a' 
  AND token = 'HUlmr0O6bBPSamVadvf3/Y30SHl9wpeeaZ5/CHoIwcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}