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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9a634e55a020afdf174858f3f0c16ebaf70567830217bfbf3e09efed73fb1c6e' 
  AND token = 'zINoPlY5jUWNZTdtMr9VIx2A2GHoEFdkGegPNaaMOBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}