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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '442d86b458c4d4b21d444b11c24648b6db01d5f6c359de9340c5365bb8c400cc' 
  AND token = 'UOga/o5Q8/qOZ4yvamYZ75FO/g5YYlgPFcZ41pp/JbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}