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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8cb2d48d27e6fca820882d1e3bfcae04a9f6f01472d38a24136fedb37b01020b' 
  AND token = 'aT/xox5zcMRHXxjFY8X+ACA8tkhGAySHjENIHW5k4Ps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}