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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2bdef5a1d85ede53ca3292d5b130e69fb82cf049208e06b0b70ace5caafff3e0' 
  AND token = '0OSOOBLJGJP67/vDogiouY5fkZyyELiqDTsFCsPJbc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}