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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e55201bdd1576cad24fb545c5416e0d4850617bfbade902b6f29252172b71fca' 
  AND token = 'DB2/YaxQsF9uhDkpCE3cxe2382c3pdEAhbFpvInuoAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}