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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cfd72d6cbbe9f1b476ff2897c26a471d5589c994843e6d58edea53935de85427' 
  AND token = 'OaX6IOCCEakKptgaxFw5t+LtLJceG0AEFwcfu0yOQYY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}