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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e340f57c026fe52c12f77a44ed8e086dcac0dd81b24c28df0e263048069ab608' 
  AND token = 'q6VRyQiP8S2A0iiOwRW1EEZLJZiXUxhomr1cs0XS5DY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}