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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '45e06264cfb3953713796e545c3965c8e7c1abb343af48b1eee835c05a03152c' 
  AND token = 'o+8QSZKyIT67S1cS9zPwOTGtrVX3/Eo4pjiMPxYe2Pw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}